Liquid medication injection device

ABSTRACT

Provided is a liquid medicine injection device having a needle holder slid immediately by using the elasticity of a spring such that a needle installed at the needle holder may be instantly inserted into a patient.

TECHNICAL FIELD

The present disclosure relates to liquid medicine injection devices.

BACKGROUND ART

Liquid medicine injection devices such as insulin injection devices areused to inject liquid medicines into the bodies of patients, which areused by professional medical staff such as nurses or doctors but aremostly used by ordinary persons such as caretakers or patientsthemselves. Since the liquid medicines injected through the liquidmedicine injection devices are often required to be taken by thepatients for a long period of time, the patients may suffer the pain ofthe needles of the liquid medicine injection devices being inserted manytimes.

A liquid medicine injection device has a needle for discharging liquidmedicine, and the needle should be inserted into the body of thepatient, and in this process, the patient may inevitably suffer the paindue to the insertion of the needle. In addition, the pain due to theinsertion of the needle may cause the patient to have fear of the liquidmedicine injection device and thus the objection to the liquid medicineinjection device.

DESCRIPTION OF EMBODIMENTS Technical Problem

Provided is a liquid medicine injection device that may minimize thepain and fear due to the insertion of a needle.

Solution to Problem

According to an aspect of the present disclosure, a liquid medicineinjection device includes: a casing: a button exposed outside thecasing; a needle holder located in the casing and coupled to a needle; aspring located in the casing and interposed between the button and theneedle holder; and a guiding member located in the casing to support theneedle holder.

The needle holder may be provided to rotate by an operation of thebutton, and the needle holder may include: a first support supported bythe guiding member in a first state; and a guiding groove provided to beadjacent to the first support and to pass the guiding membertherethrough in a second state where the needle holder is rotated fromthe first state.

The first support may include: a support groove formed at a surfacefacing an insertion direction of the needle and connected to the guidinggroove; and a support stopper located between the support groove and theguiding groove to provide a resistance to the rotation of the needleholder.

The guiding member may include a second support provided to support thefirst support in the first state.

The second support may include a 2-1st support portion locateddownstream with respect to a rotation direction of the needle holder anda 2-2nd support portion located upstream with respect to the rotationdirection of the needle holder, and the 2-1st support portion may belocated more adjacent to the button than the 2-2nd support portion.

The button may be provided to slide in a direction facing the needleholder, and the liquid medicine injection device may further include astopper located adjacent to the guiding member and provided to controlthe sliding of the button.

The button may include a first coupling portion protruding toward theneedle holder, and the needle holder may include a second couplingportion provided to couple to the first coupling portion.

According to another aspect of the present disclosure, a liquid medicineinjection device includes: a casing including a base: a button exposedoutside the casing; a needle holder located in the casing; and a springlocated in the casing and interposed between the button and the needleholder, wherein the needle holder is provided to be located spaced apartfrom the base of the casing in a first state, and the needle holder isprovided to be driven toward the base by the elasticity of the springwhile being transformed into a second state where the needle holder isrotated from the first state.

The liquid medicine injection device may further include a guidingmember provided to support the needle holder to be spaced apart from thebase in the first state and to guide the needle holder in the secondstate.

The needle holder may include: a first support supported by the guidingmember in the first state; and a guiding groove provided to be adjacentto the first support and to pass the guiding member therethrough in thesecond state where the needle holder is rotated from the first state.

The guiding member may include a second support provided to support thefirst support in the first state.

Advantageous Effects of Disclosure

According to the embodiments of the present disclosure described above,since the needle holder may be immediately slid by using the elasticityof the spring, the needle installed at the needle holder may beinstantly inserted into the patient.

Due to the instant insertion of the needle, the pain of the patient maybe minimized and the patient's fear for the needle may be reduced.

Accordingly, the objection to the liquid medicine injection device bythe patient having to be provided with the liquid medicine for a longperiod of time may be reduced, and the liquid medicine may be smoothlyinjected into the patient, thus contributing to the health and/ortreatment of the patient.

BRIEF DESCRIPTION OF DRAWINGS

FIG. 1 is a perspective view of a liquid medicine injection deviceaccording to an embodiment.

FIG. 2 is an exploded perspective view of the liquid medicine injectiondevice illustrated in FIG. 1.

FIG. 3 is a perspective view of a button according to an embodiment.

FIG. 4 is a bottom perspective view of the button illustrated in FIG. 3.

FIG. 5 is a perspective view of a needle holder according to anembodiment.

FIG. 6 is a side view of the needle holder illustrated in FIG. 5.

FIG. 7 is a bottom view of the needle holder illustrated in FIG. 5.

FIG. 8 is a perspective view of a second casing according to anembodiment.

FIG. 9 is a plan view of the second casing illustrated in FIG. 8.

FIG. 10 is a partial perspective view illustrating a portion of thesecond casing illustrated in FIG. 8.

FIGS. 11A and 11 B are diagrams illustrating the states of a needleholder and a guiding member in a first state and a second state,respectively.

FIG. 12 is a perspective view of a needle cover assembly according to anembodiment.

MODE OF DISCLOSURE

The present disclosure may include various embodiments andmodifications, and certain embodiments thereof are illustrated in thedrawings and will be described herein in detail. The effects andfeatures of the present disclosure and the accomplishing methods thereofwill become apparent from the following description of the embodimentstaken in conjunction with the accompanying drawings. However, thepresent disclosure is not limited to the embodiments described below,and may be embodied in various modes.

Hereinafter, embodiments of the present disclosure will be described indetail with reference to the accompanying drawings. In the followingdescription, like reference numerals will denote like elements, andredundant descriptions thereof will be omitted.

As used herein, the singular forms “a”, “an”, and “the” are intended toinclude the plural forms as well, unless the context clearly indicatesotherwise.

It will be understood that the terms “comprise”, “include”, and “have”used herein specify the presence of stated features or components, butdo not preclude the presence or addition of one or more other featuresor components.

It will be understood that when a layer, region, or component isreferred to as being “formed on” another layer, region, or component, itmay be directly or indirectly formed on the other layer, region, orcomponent. That is, for example, intervening layers, regions, orcomponents may be present.

When a certain embodiment may be implemented differently, a particularprocess order may be performed differently from the described order. Forexample, two consecutively described processes may be performedsubstantially at the same time or performed in an order opposite to thedescribed order.

Sizes of components in the drawings may be exaggerated for convenienceof description. In other words, since sizes and thicknesses ofcomponents in the drawings are arbitrarily illustrated for convenienceof description, the following embodiments are not limited thereto.

FIG. 1 is a perspective view of a liquid medicine injection deviceaccording to an embodiment.

A liquid medicine injection device 100 according to an embodiment mayinclude a button 120 exposed at one side thereof and a needle coverassembly 190 provided at the other side thereof.

The button 120 may be provided and exposed to a user such that thebutton 120 may be pressed and/or rotated by the user. The needle coverassembly 190 may be provided to protect a needle and may be separatedwhen the user uses the liquid medicine injection device 100.

The above-described liquid medicine injection device may be moreparticularly configured as illustrated in FIG. 2.

A liquid medicine injection device according to an embodiment mayinclude a casing, and the casing may include a first casing 110 and asecond casing 150 coupled to each other.

The first casing 110 may be exposed to the user even after the liquidmedicine injection device is installed at the body of the user, and anopening 111 may be formed at a portion of the first casing 110. Thebutton 120 may pass through the opening 111, and the button 120 may beexposed to the user.

The button 120, a spring 130, a needle holder 140, a pump 160, and aliquid medicine storage unit 170 may be located between the first casing110 and the second casing 150 coupled to each other, that is, inside thecasing.

Although not illustrated, the liquid medicine storage unit 170 mayinclude a storage tank for storing liquid medicine and a piston fordischarging the liquid medicine; however, the present disclosure is notlimited thereto and the liquid medicine storage unit 170 may includeonly the storage tank. The liquid medicine may be a liquid includingmedicine such as insulin.

The liquid medicine storage unit 170 may be connected to the pump 160through a liquid connection member such as a tube. The pump 160 may beconfigured to pump the liquid medicine toward the needle holder 140 andmay pump a certain amount of liquid medicine according to a pumpingcycle. The pump 160 may be electrically connected to a separate powersupply and a controller (not illustrated) to suck the liquid medicinefrom the liquid medicine storage unit 170 and discharge the suckedliquid medicine to the needle holder 140.

The pump 160 may include any types of pumps having a liquid medicinesuction force and a liquid medicine discharge force by electricity. Forexample, the pump 160 may include any types of pumps such as amechanical displacement type micropump and an electromagnetic motiontype micropump. The mechanical displacement type micropump may be a pumpthat uses solid or fluid motion such as a gear or diaphragm to generatea pressure difference to induce fluid flow, examples of which mayinclude a diaphragm displacement pump, a fluid displacement pump, and arotary pump. The electromagnetic motion type micropump may be a pumpthat uses electric or magnetic energy for fluid movement, examples ofwhich may include an electro-hydrodynamic pump (EHD), an electro-osmoticpump, a magneto-hydrodynamic pump, and an electro-wetting pump.

The pump 160 may be connected to the needle holder 140 through a tube TUand a connector CN. The tube TU connected to the pump 160 may beconnected to the connector CN and it may be connected to a needle NDwhile being supported by the needle holder 140. Thus, the liquidmedicine discharged from the pump 160 may be discharged through theneedle ND through the tube TU and the connector CN. For this purpose,the needle holder 140 may be coupled to the needle ND.

The needle holder 140 may be arranged to face the button 120, and thespring 130 may be interposed between the needle holder 140 and thebutton 120. The button 120, the spring 130, and the needle holder 140may be arranged along an axis AX. The axis AX may be parallel to a Zaxis in the drawings.

In the embodiment illustrated in FIG. 2, the liquid medicine storageunit 170 and the pump 160 are schematically illustrated and are notlimited to the illustrated shapes and/or arrangements.

FIGS. 3 and 4 are respectively a perspective view and a bottomperspective view of the button 120 according to an embodiment.

The button 120 may be formed in a substantially cylindrical shape andmay be provided to rotate on the axis AX along a rotation direction R1.A rotation groove 122 may be formed at a surface 121 of the button 120in a Z-axis direction such that the user may easily rotate the button120. The user may easily rotate the button 120 by inserting a nail or acoin into the rotation groove 122.

The button 120 may have a cylindrical side surface 123, and a ringmember OR may be inserted near the top of the side surface 123. AnO-ring may be used as the ring member OR to prevent the liquid medicinefrom leaking between the button 120 and the opening 111 of the firstcasing 110. Alternatively, the ring member OR may provide a certainresistance to the pressure when the button 120 is pressed by the userand/or prevent the button 120 from protruding easily after beingpressed.

As illustrated in FIGS. 3 and 4, a fastening opening 127 may be formedat the side surface 123. At least one pair of fastening openings 127 maybe provided at mutually symmetrical portions of the side surface 123.The fastening opening 127 may be located at a substantially centralportion of the side surface 123 in the Z-axis direction, and thus, afastening rod 123 a may be formed at an edge of the fastening opening127. The fastening opening 127 may be fastened to a stopper (which willbe described below), and in this case, the fastening rod 123 a may becaught by the stopper to prevent the button 120 from being detached. Thefastening opening 127 may be formed to extend in an X-Y plane directionalong an outer circumferential surface of the side surface 123 such thatthe button 120 may rotate along the rotation direction R1 while beingfastened to the stopper.

A first groove 128 a may be formed at a portion of the side surface 123adjacent to the fastening opening 127. The first groove 128 a may belocated on both sides of each fastening opening 127 to provide a certainelasticity when the fastening opening 127 is fastened to the stopper.

A second groove 128 b may be further formed at the side surface 123, andwhen the button 120 is coupled to the needle holder 140, the connectorCN may penetrate the side surface 123 through the second groove 128 b.

As illustrated in FIG. 4, a first coupling portion 125 may be providedat an inner surface of the button 120, for example, at a surface facingthe needle holder 140. The first coupling portion 125 may be coupled toa second coupling portion of the needle holder 140 (which will bedescribed below). The first coupling portion 125 may include a 1-1stcoupling protrusion 125 a and a 1-2nd coupling protrusion 125 b thatprotrude toward the needle holder 140 and face each other while beingspaced apart from each other, and a gap 125 c may be provided betweenthe 1-1st coupling protrusion 125 a and the 1-2nd coupling protrusion125 b. The first coupling portion 125 may not be fixedly fastened to thesecond coupling portion (which will be described below and may be anytype that may engage with the second coupling portion when the userpresses the button 120 and may transmit the rotational force of thebutton 120 to the needle holder 140 when the user rotates the button120.

FIGS. 5 to 7 are respectively a perspective view, a side view, and abottom view of the needle holder 140 according to an embodiment.

The needle holder 140 according to an embodiment may have asubstantially disk-shaped body 141 to rotate easily along the rotationdirection R1. As described above, the connector CN connected to the pump160 may be coupled to the body 141

The needle ND may be coupled to the body 141 in a direction opposite tothe button 120, and the needle ND may be connected to the connector CNto communicate with the tube TU. As illustrated in FIG. 7, the needle NDmay be located at the center of a bottom surface 149 of the body 141.

On the opposite side of a portion of the body 141 coupled to theconnector CN, a support 145 may be erected in the Z-axis direction. Thesupport 145 may be formed in a circumferential direction along an edgeof the body 141. The support 145 may prevent the needle holder 140 frombeing tilted to one side by the tension of the tube TU and may guide theneedle holder 140 to move linearly along an insertion direction K of theneedle ND.

A second coupling portion 142 may be provided at a surface of the body141 facing the button 120.

The second coupling portion 142 may be coupled to the first couplingportion 125. The second coupling portion 142 may include a 2-1stcoupling protrusion 142 a and a 2-2nd coupling protrusion 142 b thatprotrude toward the button 120 while being spaced apart from each other.The 2-1st coupling protrusion 142 a and the 2-2nd coupling protrusion142 b may be any type that may engage with the first coupling portion125 when the user presses the button 120 and may transmit the rotationalforce of the button 120 to the needle holder 140 when the user rotatesthe button 120. For example, when the first coupling portion 125 and thesecond coupling portion 142 are coupled to each other, the gap 125 cbetween the 1-1st coupling protrusion 125 a and the 1-2nd couplingprotrusion 125 b may be inserted between the 2-1st coupling protrusion142 a and the 2-2nd coupling protrusion 142 b. Accordingly, the firstcoupling portion 125 and the second coupling portion 142 may be engagedwith each other.

The first coupling portion 125 may be inserted into one end of thespring 130 illustrated in FIG. 2 and the second coupling portion 142 maybe inserted into the other end of the spring 130, so that the spring 130may be fixed between the button 120 and the needle holder 140. Thespring 130 may be coupled between the button 120 and the needle holder140 in a compressed state to some degree; however, the presentdisclosure is not limited thereto and the spring 130 may be interposedbetween the button 120 and the needle holder 140 in a normal state thatis an uncompressed state in a state where the user does not press thebutton 120.

The needle holder 140 may include a first support 146 and a guidinggroove 144.

The first support 146 may be supported by a guiding member 155 (see FIG.8) (which will be described below) in a first state before the needleholder 140 rotates and may be located spaced apart from a base 151 ofthe second casing 150 by a certain distance. That is, in the firststate, the needle holder 140 may float to some degree from the base 151in the Z-axis direction.

The guiding groove 144 may be located adjacent to the first support 146.As illustrated in FIGS. 5 to 7, the guiding groove 144 may be locatedadjacent to the first support 146 in the opposite direction to therotation direction R1. The guiding groove 144 may be formed at the body141 in a cut shape with a certain width. The guiding groove 144 may beprovided to penetrate the body 141 in the needle (ND) insertiondirection K, for example, in the Z-axis direction of the drawings. Theguiding groove 144 may be provided to pass the guiding member 155 (whichwill be described below) therethrough in a second state where the needleholder 140 is rotated. That is, in the second state, the guiding member155 may be inserted into the guiding groove 144, and in this case, theneedle holder 140 may be slid by the spring 130 along the needle (ND)insertion direction K.

The first support 146 may include a support groove 146 a formed in theshape of a groove having a certain depth in the Z-axis direction on thesurface of the body 141 facing the insertion direction K. The supportgroove 146 a may be connected to the guiding groove 144, and a supportstopper 146 b may be located between the support groove 146 a and theguiding groove 144. The support stopper 146 b may have the shape of aprotrusion protruding in a direction opposite to the direction in whichthe support groove 146 a is formed. The guiding member described belowmay be supported at the support groove 146 a in the first state, andwhen the needle holder 140 is transformed from the first state to thesecond state, that is, when the needle holder 140 rotates along therotation direction R1, the support stopper 146 b may provide a certaindegree of resistance to the rotation. Thus, when the user rotates thebutton 120 with a force greater than the resistance, the needle holder140 may rotate along the rotation direction R1.

FIGS. 8 and 9 are respectively a perspective view and a plan view of thesecond casing 150 according to an embodiment, and FIG. 10 is a partialperspective view illustrating a portion of the second casing 150.

The second casing 150 coupled to the first casing 110 may include a base151. The base 151 may be a portion of the second casing 150. The base151 may be formed separately from the second casing 150 and coupled tothe bottom of the second casing 150.

A needle through-hole 153 may be formed at a substantially centralportion of the base 151 to pass the needle ND therethrough.

A substantially cylindrical guide wall 152 may be formed around theneedle through-hole 153. The guide wall 152 may be provided to protrudein the Z-axis direction from the base 151 toward the first casing 110.

As illustrated in FIG. 9, a planar outer diameter of the guide wall 152may be smaller than an inner diameter of the side surface 123 of thebutton 120. Accordingly, when the button 120 is pressed, the sidesurface 123 of the button 120 may be located outside the guide wall 152and thus the button 120 may slide linearly along the guide wall 152toward the needle holder 140, that is, along the needle insertiondirection K.

As illustrated in FIGS. 8 and 10, a portion of the guide wall 152 mayhave formed therein a cut groove 152 h cut from the base 151 to theopposite end thereof. The connector CN of the needle holder 140 may passthrough the cut groove 152 h.

A guiding member 155 may be provided on an inner surface of the guidewall 152. The guiding member 155 may be formed to extend in the needleinsertion direction K, for example, along the Z-axis direction in FIG.8, and may be formed in a rail shape. The guiding member 155 may beinserted into the guiding groove 144 in the second state describedabove, and the needle holder 140 may be slid in the insertion directionK along the guiding member 155.

A second support 154 provided to support the first support 146 in thefirst state described above may be formed at one end of the guidingmember 155, that is, at the end of the guiding member 155 facing thefirst casing 110. As illustrated in FIG. 10, the second support 154 mayinclude a 2-1st support portion 154 a and a 2-2nd support portion 154 b.The 2-1st support portion 154 a and the 2-2nd support portion 154 b maybe connected to each other. The 2-1st support portion 154 a may belocated downstream with respect to the rotation direction of the needleholder 140, and the 2-2nd support portion 154 b may be located upstreamwith respect to the rotation direction of the needle holder 140. In thiscase, since the 2-1st support portion 154 a is located more adjacent tothe button 120 than the 2-2nd support portion 154 b, when the needleholder 140 rotates along the rotation direction R1, a certain degree ofresistance may be provided to the rotation. Thus, when the user rotatesthe button 120 with a force greater than the resistance, the needleholder 140 may rotate along the rotation direction R1.

A stopper 157 may be formed on an outer surface of the guide wall 152.The stopper 157 may be a protrusion protruding in the X-axis directionfrom the outer surface of the guide wall 152. As illustrated in FIG. 10,the stopper 157 may extend in the X-Y plane direction along an outercircumferential surface of the guide wall 152.

The stopper 157 may be provided to control the sliding of the button 120in the Z-axis direction and may include a first stopper 157 a and asecond stopper 157 b that are spaced apart in parallel along the Z-axisdirection. The first stopper 157 a and the second stopper 157 b may beinserted into the fastening opening 127 of the button 120 illustrated inFIGS. 3 and 4, and the fastening rod 123 a may be caught by the firststopper 157 a and the second stopper 157 b to prevent the button 120from being detached in the direction opposite to the insertion directionK. The first stopper 157 a may be fastened to the fastening opening 127in a state before the button 120 is pressed, and the second stopper 157b may be fastened to the fastening opening 127 in a state where thebutton 120 is pressed.

In the liquid medicine injection device 100 according to an embodimentconfigured as described above, when the user presses the button 120 in astate where the outer surface of the second casing 150 is located at aregion where the user will use the liquid medicine injection device 100,the button 120 and the needle holder 140 may be coupled to each other,and when the user rotates the button 120, the needle holder 140 may beslid in the needle (ND) insertion direction K by the elasticity of thespring 130 to instantly insert the needle ND. In this case, the spring130 may be sufficiently compressed according to the pressing of thebutton 120, and the effect of the instant insertion of the needle ND bythe elasticity of the spring 130 may be increased. The instant insertionof the needle ND may minimize the pain and fear of the patient.

According to an embodiment, for example, as illustrated in FIG. 11A, ina first state where the needle holder 140 is not rotated, the needleholder 140 may be spaced apart from the base 151 of the second casing150. In this state, the needle ND may not be inserted into the body ofthe patient. In the first state, the first support 146 of the needleholder 140 may contact and support the second support 154 of the guidingmember 155. In this case, according to an embodiment, the first support146 and the second support 154 may engage with each other and thus thesupport groove 146 a and the 2-1st support portion 154 a may contacteach other and the support stopper 146 b and the 2-2nd support portion154 b may contact each other. Thus, in the first state, the needleholder 140 may be more stably supported by the end of the guiding member155.

When the user rotates the button 120 and thus the needle holder 140rotates along the rotation direction R1, the support stopper 146 b andthe 2-1st support portion 154 a may move relatively in directionsintersecting each other and thus a resistance to the rotation may beprovided to the needle holder 140. When the user rotates the button 120with a force exceeding the resistance and thus a rotational forceexceeding the resistance is applied to the needle holder 140, thesupport stopper 146 b may pass over the 2-1st support portion 154 a andthus the guiding member 155 may enter the guiding groove 144.

The guiding groove 144 and the guiding member 155 may have a first widthW1 and a second width W2 in the X-axis direction, respectively. Thefirst width W1 may exceed the second width W2 such that the guidingmember 155 may be smoothly inserted into the guiding groove 144.

Thus, as illustrated in FIG. 11B, when the user rotates the button 120and thus it becomes a second state where the needle holder 140 iscompletely rotated, the needle holder 140 may be driven toward the base151 of the second casing 150 by being slid along the guiding member 155in a state where the guiding member 155 is inserted into the guidinggroove 144 and thus the needle ND may inserted into the body of thepatient.

According to the present disclosure, since the compressed force of thespring may be instantly emitted to drive the needle holder toward thebase, the needle coupled to the needle holder may be instantly insertedinto the body of the patient.

In order to provide a resistance to the rotation of the needle holderand induce the user to apply a rotational force exceeding the resistanceto the button, the liquid medicine injection device according to theabove embodiment may include the first support 146 of the needle holderand the second support 154 of the guiding member 155; however, thepresent disclosure is not limited thereto. That is, it may not benecessary to provide a resistance to the rotation of the needle holder,and the present disclosure may also include any other configuration inwhich the needle holder may be instantly inserted into the body of thepatient by rapidly sliding the needle holder by using the elastic forceof the spring according to the rotation of the needle holder by theuser.

A liquid medicine injection device according to another embodiment mayfurther include a needle cover assembly in order to protect a needlebefore the user uses the needle.

FIG. 12 is a perspective view of the needle cover assembly 190 accordingto an embodiment.

The needle cover assembly 190 may include a cover plate 191. The coverplate 191 may be provided as a flat plate and one end thereof may beformed as a handle 191 a and thus the user may use the handle 191 a todetach the needle cover assembly 190 from the casing.

The needle cover assembly 190 may include a needle cover 192. The needlecover 192 may be inserted into the needle through-hole 153 provided atthe base 151 of the second casing 150. Although not illustrated, theneedle cover 192 may include a closed space, and a tip portion of theneedle may be inserted into the closed space. The closed space mayinclude a portion formed of a material through which air passes butliquid does not pass, or a portion capable of varying in volume, thuspreventing the liquid medicine from being discharged outside in apriming operation of the user to remove the air from the inside of theneedle and/or the inside of the tube.

Although the present disclosure has been described with reference to theembodiments illustrated in the drawings, this is merely an example andthose of ordinary skill in the art will understand that variousmodifications and other equivalent embodiments may be derived therefrom.Thus, the spirit and scope of the present disclosure should be definedby the appended claims.

INDUSTRIAL APPLICABILITY

The embodiments of the present disclosure may be applied to variousliquid medicine injection devices, such as insulin injection devices,used to inject liquid medicines into the bodies of patients.

1. A liquid medicine injection device comprising: a casing: a buttonexposed outside the casing; a needle holder located in the casing andcoupled to a needle; a spring located in the casing and interposedbetween the button and the needle holder; and a guiding member locatedin the casing to support the needle holder.
 2. The liquid medicineinjection device of claim 1, wherein the needle holder is provided torotate by actuation of the button, and the needle holder comprises: afirst support supported by the guiding member in a first state; and aguiding groove provided to be adjacent to the first support and to passthe guiding member therethrough in a second state where the needleholder is rotated from the first state.
 3. The liquid medicine injectiondevice of claim 2, wherein the first support comprises: a support grooveformed at a surface facing an insertion direction of the needle andconnected to the guiding groove; and a support stopper located betweenthe support groove and the guiding groove, the support stopperconfigured to provide resistance to the rotation of the needle holder.4. The liquid medicine injection device of claim 2, wherein the guidingmember comprises a second support provided to support the first supportin the first state.
 5. The liquid medicine injection device of claim 4,wherein the second support comprises first support portion locateddownstream with respect to a rotation direction of the needle holder anda second support portion located upstream with respect to the rotationdirection of the needle holder, and wherein the first support portion islocated more adjacent to the button than the second support portion. 6.The liquid medicine injection device of claim 1, wherein the button isprovided to slide in a direction facing the needle holder, and theliquid medicine injection device further comprises a stopper locatedadjacent to the guiding member and configured to control the sliding ofthe button.
 7. A liquid medicine injection device comprising: a casingcomprising a base: a button exposed outside the casing; a needle holderlocated in the casing; and a spring located in the casing and interposedbetween the button and the needle holder, wherein the button comprises afirst coupling portion protruding toward the needle holder, wherein theneedle holder comprises a second coupling portion provided to couple tothe first coupling portion, wherein the needle holder is configured tobe located spaced apart from the base of the casing in a first state,and wherein the needle holder is configured to be driven toward the baseby the elasticity of the spring while being transformed into a secondstate in which the needle holder is rotated with respect to the firststate.
 8. The liquid medicine injection device of claim 7, furthercomprising a guiding member configured to support the needle holder tobe spaced apart from the base in the first state and to guide the needleholder in the second state.
 9. The liquid medicine injection device ofclaim 8, wherein the needle holder comprises: a first support supportedby the guiding member in the first state; and a guiding grooveconfigured to be adjacent to the first support and to pass the guidingmember therethrough in the second state where the needle holder isrotated from the first state.
 10. The liquid medicine injection deviceof claim 9, wherein the guiding member comprises a second supportprovided to support the first support in the first state.